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Chemotherapy A type of cancer treatment using drugs that kill cancer cells and/or limit their growth anxiety exhaustion order luvox 100mg. These drugs are usually administered to the patient by slow infusion into a vein but can also be administered orally anxiety symptoms questionnaire buy luvox 100 mg, by direct infusion to the limb or by infusion to the liver anxiety 9 weeks pregnant best 100mg luvox, according to cancer location anxiety forum best luvox 50mg. Cancer or leukemia cells often have a chromosomal abnormality which is a change to their chromosomes, such as a chromosomal duplication or an extra chromosome (47 chromosomes) or have a chromosomal deletion or a loss of a chromosome (45 chromosomes). A chromosomal or genetic inversion is when no extra chromosomes are added or deleted, but instead a portion is backwards. Deep vein thrombosis the formation of a blood clot in a deep vein of the leg or lower pelvis. Diaphragm the thin muscle below the lungs and heart that separates the chest from the abdomen. The graph can show that there are abnormal conditions, such as blocked arteries, changes in electrolytes (particles with electrical charges), and changes in the way electrical currents pass through the heart tissue. Endoscopy/endoscopic A medical procedure where a doctor puts a tube-like instrument into the body to look inside. There are many types of endoscopy, each of which is designed for looking at a certain part of the body. Endoscopic ultrasound A procedure in which an endoscope is inserted into the body. An endoscope is a thin, tube-like instrument that has a light and a lens for viewing. A probe at the end of the endoscope is used to bounce high-energy sound waves (ultrasound) off internal organs to make a picture (sonogram). Epirubicin A drug used together with other drugs to treat early breast cancer that has spread to lymph nodes*. Epithelium the term "epithelium" refers to cells that line hollow organs and glands and those that make up the outer surface of the body. Esophagogram A series of x-ray pictures of the esophagus taken after a patient drinks a liquid containing barium sulfate (a form of the silver-white metallic element barium). The barium sulfate coats and outlines the inner wall of the esophagus so that it can be seen on the x-ray pictures. This includes keeping track of the health of people who participate in a clinical study or clinical trial for a period of time, both during the study and after the study ends. Gastroenterologist A doctor who specializes in diagnosing and treating disorders of the digestive system. Gastroesophageal reflux the backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the stomach). Helicobacter pylori A type of bacterium that causes inflammation and ulcers in the stomach or small intestine. Histological type the category in which a tumor is grouped, considering the characteristics of its cells and other structures under the microscope. These antigens are visualized by a marker such as fluorescent dye, enzyme, or colloidal gold. Immunohistochemical staining is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors. Intravenous usually refers to a way of giving a drug or other substance through a needle or tube inserted into a vein. Lamina propria the lamina propria is a thin layer of loose connective tissue* which lies beneath the epithelium* and together with the epithelium constitutes the mucosa*. The term mucosa or mucous membrane always refers to the combination of the epithelium plus the lamina propria. Lymph node A rounded mass of lymphatic tissue* that is surrounded by a capsule of connective tissue. Metastasis/metastase(s)/metastatic the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a metastatic tumor or a metastasis. Mucus serves to protect cells from the epithelium* in the respiratory, gastrointestinal, urinary, genital, visual, and auditory systems. Multidisciplinary opinion A treatment planning approach in which a number of doctors who are experts in different areas (disciplines) review and discuss the medical condition and treatment options of a patient. In cancer treatment, a multidisciplinary opinion may include that of a medical oncologist (who provides cancer treatment with drugs), a surgical oncologist (who provides cancer treatment with surgery), and a radiation* oncologist (who provides cancer treatment with radiation*).

Access to Expert Consult is available with the activation code provided on the inside front cover anxiety 8 weeks pregnant purchase 50mg luvox. The Primer will now fit into your pocket on a smartphone or tablet anxiety symptoms at bedtime safe luvox 50mg, delivering the information that you seek when you need it anxiety symptoms like heart attack purchase luvox 100 mg. We are grateful to the authors and editors who diligently compiled a wealth of information into thorough yet concise reviews anxiety 120 bpm trusted luvox 100mg, ensuring that the Primer maintains its clarity and brevity. We are also grateful to the publisher, designers, and copy editors who strove to create an appealing and highly accessible text with illustrative tables and figures to reinforce key messages. We hope you find the Primer to be the same go-to resource clinicians have relied on for the past 20 years. The principal job of the kidneys is the correction of perturbations in the composition and volume of body fluids that occur as a consequence of food in take, metabolism, environmental factors, and exercise. In healthy people, such perturbations are typically corrected within a matter of hours so that, in the long term, body-fluid volume and the concentrations of most ions do not deviate much from normal set points. In many disease states, however, these regulatory processes are disturbed, resulting in persistent deviations in body-fluid volume or ionic concentrations. Understanding these disorders requires an understanding of the normal regulatory processes. Maintenance of body composition: the kidney regulates the volume of fluid in the body; its osmolarity, electrolyte content, and concentration; and its acidity. It achieves this regulation by varying the amounts of water and ions excreted in the urine. Electrolytes regulated by changes in urinary excretion include sodium, potassium, chloride, calcium, magnesium, and phosphate. Excretion of metabolic end products and foreign substances: the kidney excretes a number of products of metabolism, most notably urea, and a number of toxins and drugs. Renin is an enzyme produced by the granular cells of the juxtaglomerular apparatus that catalyzes the formation of angiotensin from a plasma globulin, angiotensinogen. Angiotensin is a potent vasoconstrictor peptide that significantly contributes to salt balance and blood-pressure regulation. Erythropoietin, a glycosylated protein comprising 165 amino acids that is produced by renal cortical interstitial cells, stimulates the maturation of erythrocytes in the bone marrow. This steroid hormone plays an important role in the regulation of body calcium and phosphate balance. In later chapters of this Primer, the pathophysiologic mechanisms and consequences of derangements in kidney function are discussed in detail. This chapter reviews the basic anatomy of the kidney, the normal mechanisms for urine formation, and the physiology of sodium, potassium, water, and acid-base balance. The maintenance of stable body-fluid composition requires that appearance and disappearance rates of any substance in the body balance each other. Balance is achieved when Ingested amount + Produced amount = Excreted amount + Consumed amount For a large number of organic compounds, balance is the result of metabolic production and consumption. However, electrolytes are not produced or consumed by the body, so balance can only be achieved by adjusting excretion to match intake. Hence, when a person is in balance for sodium, potassium, and other ions, the amount excreted must equal the amount ingested. Because the kidneys are the principal organs where regulated excretion takes place, urinary excretion of such solutes closely follows the dietary intake. For example, · C ardiac output and blood pressure are dependent on optimal plasma volume. Adipose tissue is low in water content; therefore, in obese people, the fraction of body weight that is water is lower than in lean individuals. As a consequence of their slightly greater fat content, women contain a lower percentage of water on average than men-about 55% instead of 60%. Useful round numbers to remember for bedside estimates of bodyfluid volumes are provided in Table 1. Example for 60-kg Patient 60% Ч 60 kg = 36 L 2 /3 Ч 36 L = 24 L 1 /3 Ч 36 L = 12 L ј Ч 12 L = 3 L 3 L ч (1 - 0. The human kidney is made up of approximately one million nephrons, two of which are shown schematically here. Each nephron consists of the following parts: glomerulus (1), proximal convoluted tubule (2), proximal straight tubule (3), thin descending limb of the loop of Henle (4), thin ascending limb (5), thick ascending limb (6), macula densa (7), distal convoluted tubule (8), and connecting tubule (9).

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See also organophosphates and carbamates anxiety symptoms psychology luvox 100mg, 291­295 hazard summary for anxiety symptoms long term proven 50 mg luvox, 551t toxicity of anxiety symptoms 4 days effective luvox 100 mg, 292t Difenacoum anxiety pain buy luvox 50mg. See also warfarin, 378­380 in rodenticides, 378­380 toxicity of, 378­380 Difenoxin, with atropine (Motofen), 246­247 Diflunisal. See also hallucinogens, 247­249; plants, 309­319 1,3-Dihydroxybenzene (resorcinol). See also phenols, 302­303 hazard summary for, 609t 1,4-Dihydroxybenzene (hydroquinone). See also phenols, 302­303 hazard summary for, 580t toxicity of, 302 Diisobutyl ketone, hazard summary for, 564t Diisopropylamine, hazard summary for, 564t Diisopropyl ether (isopropyl ether), hazard summary for, 583t 2,6-Diisopropylphenol (propofol), 494­496 pharmacology/use of, 494­496 for seizures, 24, 494­496 Dilacor. See also phenytoin, 303­305, 488­489 pharmacology/use of, 488­489 toxicity of, 303­305 Dilaudid. See also calcium antagonists, 144­147 hypotension caused by, 16t pharmacokinetics of, 387t toxicity of, 144, 145t in toxicology screens, 41t, 146 Dimaval. See also caustic and corrosive agents, 157­159 binding agent for, 53t elimination of, 56t, 297 hazard summary for, 600t hypoxia caused by, 7t oxygen therapy contraindications and, 298, 483 pharmacokinetics of, 297 toxicity of, 158t, 296­298 volume of distribution of, 56t, 297 2,3-Dimethyl-butane (hexane isomer), hazard summary for, 578t 1,3-Dimethylbutyl acetate (sec-hexyl acetate), hazard summary for, 578t Dimethylcarbamoyl chloride, hazard summary for, 564t 658 Dimethyl cis-2-dimethylcarbamoyl-1-methylvinyl phosphate (dicrotophos). See also organophosphates and carbamates, 291­295 hazard summary for, 562t toxicity of, 292t Dimethyldithiocarbamate, ferric (ferbam), hazard summary for, 574t O,O-Dimethyl dithiophosphate of diethyl mercaptosuccinate (malathion). See also organophosphates and carbamates, 291­295 hazard summary for, 595t toxicity of, 292t O,O-Dimethyl O-(3-methyl-4-[methylthio]phenyl)phosphorothioate (fenthion). See also organophosphates and carbamates, 291­295 toxicity of, 293t Dioxane/1,4-dioxane. See also glycols, 194­198 hazard summary for, 566t toxicity of, 196t Dioxathion (2,3-p-dioxanedithiol S,S-bis [O,O-diethyl phosphorodithioate]), hazard summary for, 566t Dioxins, toxicity of, 184­186 Diphacinone. See also warfarin, 378­380 in rodenticides, 378­380 toxicity of, 378­380 Diphenhydramine, 436­437. See also warfare agents, chemical, 372­378 toxicity of, 375t Diphenyl benzenes (terphenyls), hazard summary for, 616t Diphenyl ether (phenyl ether), hazard summary for, 602t 4,4-Di-phenylmethane diisocyanate (methylene bisphenyl isocyanate), hazard summary for, 590t Diphenyl oxide, chlorinated, hazard summary for, 548t Diphenylpyraline. See paraquat and diquat, 296­298 Diquat, 296­298 coma caused by, 19t hazard summary for, 567t pharmacokinetics of, 297 stupor caused by, 19t toxicity of, 296­298 Direct-current countershock for ventricular fibrillation, 15 for ventricular tachycardia without pulse, 15 "Dirty bomb. See also nontoxic products, 286 accidental exposure to , 287t Distribution, volume of (Vd), accessibility to removal by enhanced elimination and, 54, 55t, 56t Disulfiram, 186­187 carbon disulfide as metabolite of, 150, 186 atherosclerotic disease and, 523 chemical coexposures and, 524 coma caused by, 19t, 186 confusion caused by, 24t, 186 delirium caused by, 24t ethanol interaction and, 186, 187, 445 hazard summary for, 567t mushroom intoxication and, 272t neuropathy caused by, 31t pharmacokinetics of, 186, 387t stupor caused by, 19t, 186 teratogenic effects of, 59t toxicity of, 186­187 warfarin interaction and, 379t Disulfoton (O,O-diethyl-S-ethylmercapto-ethyl dithiophosphate). See also organophosphates and carbamates, 291­295 hazard summary for, 567t toxicity of, 292t Disulfur decafluoride (sulfur pentafluoride), hazard summary for, 615t Dithiophosphate, O,O-diethyl-S-ethylmercapto-ethyl (disulfoton). See also organophosphates and carbamates, 291­295 hazard summary for, 567t toxicity of, 292t Ditropan. See hydroflumethiazide, 188t Diuresis forced, for enhanced elimination, 55 in barium poisoning, 127 osmotic, for arsine gas poisoning, 120 Diuretics, 187­189, 188t hypokalemia caused by, 38t, 39, 188 for hyponatremia, 37 hyponatremia caused by, 36t thiazide hyperglycemia caused by, 35t, 188 toxicity of, 188t toxicity of, 187­189, 188t Diuril. See also amphetamines, 72­74; hallucinogens, 247­249 toxicity of, 73, 248t, 249 Docetaxel. See also antineoplastic agents, 100­107 toxicity of, 103t Dofetilide, ventricular arrhythmias caused by, 14t Dogbane, 313t. See also plants, 309­319 Dolasetron, ventricular arrhythmias caused by, 14t Dolls-eyes, 313t. See also hallucinogens, 247­249 toxicity of, 248t, 249 Domoic acid, food poisoning caused by (amnestic shellfish poisoning), 205­207, 206t Donnatal. See atropine, 85t, 412­413 hyoscyamine, 85t phenobarbital, 126, 486­487 L-Dopa, monoamine oxidase inhibitor interaction and, 270t Dopamine, 438­439 for hypotension, 16, 17, 438­439 mydriasis caused by, 30t pharmacology/use of, 438­439 Dormir. See also neuromuscular blocking agents, 472­475 pharmacology/use of, 473t, 475 Doxazosin hypotension caused by, 16t pharmacokinetics of, 387t toxicity of, 365­366 Doxepin. See also tricyclic antidepressants, 90­93 pharmacokinetics of, 387t toxicity of, 88t in toxicology screens, 41t Doxil. See also antineoplastic agents, 100­107 acetylcysteine for poisoning caused by, 405­407 extravasation of, 106 toxicity of, 101t, 106 Doxycyline, for biological warfare agents, 372 Doxylamine. See caustic and corrosive agents, 157­159 sodium hydroxide, 613t Drano Liquid Drain Opener. See caustic and corrosive agents, 157­159 hypochlorite, 162­164 sodium hydroxide, 613t Drixoral. See antihistamines (dexbrompheniramine), 96­98 decongestants, (d-isoephedrine sulfate), 320­322 Dronabinol, 252. See also marijuana, 252­254 pharmacokinetics of, 253, 387t toxicity of, 252, 253 660 Droperidol, 451­453.

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